Imetelstat Sodium - NCI - National Cancer Institute
Imetelstat sodium works by blocking the activity of an enzyme called telomerase, which is found at high levels in cells that divide rapidly, including cancer cells. Blocking this enzyme keeps …
Oncology Drug Reference Sheet: Imetelstat - ons.org
Mar 18, 2025 · In June 2024, imetelstat (Rytelo™) became the first telomerase inhibitor approved by the U.S Food and Drug Administration (FDA). Imetelstat treats low- to intermediate-risk …
Imetelstat (Rytelo): a promising treatment for adults with lower …
The injectable oligonucleotide telomerase inhibitor Imetelstat is the first drug of its kind, as it functions by attaching to the telomerase enzyme, preventing telomere binding and blocking its …
Imetelstat (Rytelo™) - OncoLink
Jun 16, 2024 · Imetelstat (Rytelo™) is a telomerase inhibitor.How To Take Imetelstat Imetelstat is given intravenously (into a vein). The amount given and schedule are based on your size. You …
Rytelo: Uses, Dosage, Side Effects, Warnings - Drugs.com
Jul 16, 2024 · Rytelo (imetelstat) is an injectable telomerase inhibitor that may be used to treat adults with low- to intermediate-1 risk myelodysplastic syndromes (MDS) with transfusion …
RYTELO® (imetelstat) HCP Website | RYTELOHCP
RYTELO® (imetelstat) is indicated for treatment of adult patients with low- to intermediate-1 risk myelodysplastic syndromes (MDS) with transfusion-dependent anemia.
Geron Corporation - Geron Corporation Presents New Data at …
2 days ago · Geron Corporation Presents New Data at ASH 2025 Highlighting the Relationship Between Treatment-Emergent Cytopenias and Clinical Benefit of RYTELO® (Imetelstat) in …
6 days ago · In this report, we review the latest progress in human telomerase structure and outline emerging therapeutic strategies targeting telomerase. KEYWORDS telomerase, …
Imetelstat: First Approval | Drugs - Springer
Aug 20, 2024 · Imetelstat (RYTELO™), an oligonucleotide telomerase inhibitor, is being developed by Geron Corporation for the treatment of myeloid hematologic malignancies. In …
Annals of Medicine and Surgery - journals.lww.com
Sep 3, 2025 · The recent FDA approval of Imetelstat marks a significant advancement in the treatment of lower-risk myelodysplastic syndrome (MDS), a clonal hematopoietic disorder …