A monoclonal antibody (mAb, more rarely called moAb) is an antibody produced from a cell lineage made by cloning a unique white blood cell. All subsequent antibodies derived this way trace back to …

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Jun 3, 2025 · The mAb (ibritumomab) delivers a radioactive substance (Yttrium-90) directly to cancer cells. Another example is Kadcyla, an mAb that is attached to a chemotherapy drug.

Nov 16, 2021 · The generic names of the products often include the letters “mab” at the end of the name. What is the difference between monoclonal antibodies and polyclonal antibodies?

Bevacizumab (Avastin) is an mAb that targets a protein called VEGF that affects tumor blood vessel growth. It can cause side effects such as high blood pressure, bleeding, poor wound healing, blood …

Nov 12, 2024 · Monoclonal antibodies are a type of synthetic, human-made, antibody. They work similarly to antibodies that the body naturally produces, binding only to specific antigens.

Apr 19, 2023 · A monoclonal antibody (mAb) is a type of immune protein produced in a lab that binds to a specific protein on a cell called an antigen. As with naturally occurring antibodies, monoclonal …

Aug 12, 2025 · According to the FDA, axalitimab is a humanized mAb used to treat children and adults with chronic graft-versus-host disease (GVHD), a complication that can occur after receiving a bone …

Jun 12, 2021 · In recent years, mAb products have dominated the biotherapeutics market, with hundreds of novel mAbs and mAb-like proteins now in clinical development for the treatment of diseases in …

Jun 26, 2023 · The nomenclature of mAbs depends on the origin of each respective mAb. Common suffixes include -omab, -ximab, -zumab, and -umab, representing murine, chimeric, humanized, and …