Selectins mediate leukocyte rolling and prime leukocytes for integrin-mediated leukocyte adhesion. However, neither the in vivo importance of nor the signaling pathway by which selectin-mediated ...

For double immunofluorescence, acetone-fixed frozen sections were blocked with 10% skim milk for 15 minutes and then treated with anti-α4β7 integrin monoclonal antibody (mAb) for 90 minutes at room ...

The immune system plays a dual role in inflammation and cancer development. Immune system effector cells quickly identify and destroy malignant cells, but immune system-mediated inflammation regulates ...