Memorial Sloan Kettering Cancer Center researchers have identified a metabolic switch that determines whether intestinal stem cells become absorptive or secretory cells. Manipulating the enzyme OGDH ...
Top: Intestinal stem cells lacking Daam1 (left) or Rnf43 (right) form tumor-like organoids. Bottom: Intestines lacking Daam1 do not form ectopic Paneth cells, a type of secretory cells (left), while ...
Ram P. Chakrabarty is in the Department of Medicine, Division of Pulmonary and Critical Care Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois 60611, USA. Navdeep S.
Stem cells can differentiate to replace dead and damaged cells. But how do stem cells decide which type of cell to become in a given situation? Using intestinal organoids, the group of Bon-Kyoung Koo ...
A type of flatworms, called planarians, can regenerate whole organisms from pieces as small as one-279th of their body. 1 Depending on how these goofy-looking worms were cut, they could even come back ...
Stem cells can differentiate to replace dead and damaged cells. But how do stem cells decide which type of cell to become in a given situation? Using intestinal organoids, scientists identified a new ...
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