Proceedings of the National Academy of Sciences of the United States of America, Vol. 118, No. 32 (August 10, 2021), pp. 1-11 (11 pages) Family with sequence similarity 20C (Fam20C), the major protein ...
A novel reporter protein has been developed to enable the investigation of protein biogenesis in the ER and its disruption in disease. A recent research collaboration between multiple Japanese ...
Osaka, Japan – Our cells carry out hundreds of thousands of important functions every day, all of which are carefully orchestrated at a microscopic scale. However, the precise mechanisms that ...
Autophagy and lysosomal pathways orchestrate unconventional secretion of Parkinson’s disease protein
Oxidative stress induced by 6-OHDA stimulates autophagy flux, which enhances STX17-mediated autolysosome formation, leading to the degradation of autophagosomal contents. However, in response to ...
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