Adhesion molecules are pivotal mediators of cell–cell and cell–matrix interactions that underpin immune surveillance, vascular integrity and tissue homoeostasis. In the cardiovascular system, members ...
The immune system plays a dual role in inflammation and cancer development. Immune system effector cells rapidly recognize and kill malignant cells; meanwhile, immune system-mediated inflammation ...
Cells are the fundamental unit of life. The average human body contains around 30 trillion cells with varying functions and potentials. Communication between cells is central to the body’s ability to ...
Cell adhesion molecules are ubiquitous, specifying precise cell–cell interactions in many, diverse, cellular processes. Now, researchers have engineered molecules that act like “cellular glue,” ...
Our bodies comprise different tissues and organs, which are composed of many cells that must adhere to form functional higher order structures. This adherence is facilitated by specialized proteins ...
This year’s Lasker Basic Medical Research Award recognizes the contributions of Drs. Richard Hynes, Erkki Ruoslahti, and Timothy Springer for their discovery and characterization of integrins, a major ...
Announcing a new article publication for Cardiovascular Innovations and Applications journal. Vascular Adhesion Molecules (VAMs) appear to play important roles in the development of Cardiovascular ...
CytomX is advancing its ADC candidate CX-2051 in the oncological field. CX-2051 shows an impressive response rate and improved progression-free survival in heavily pretreated colorectal cancer ...
Efficacy of sorafenib in patients with oligometastatic hepatoceulluar carcinoma (HCC). This is an ASCO Meeting Abstract from the 2015 ASCO Annual Meeting I. This abstract does not include a full text ...
Electrical synapses containing Connexin 36 (Cx36) represent the main means for direct electrical communication among neurons in the mammalian nervous system. However, little is kn ...
The immune system plays a dual role in inflammation and cancer development. Immune system effector cells quickly identify and destroy malignant cells, but immune system-mediated inflammation regulates ...