Gene therapy holds the promise of preventing and curing disease by manipulating gene expression within a patient's cells. However, to be effective, the new gene must make it into a cell's nucleus. The ...

A recent international research project has used advanced microscopy techniques and computational modeling to discover why ...

Within a cell, the nucleus is surrounded by the nuclear envelope—two layers of phospholipid membrane that prevents the nucleus mixing with other parts of the cell, thus protecting the cell's DNA from ...

A research group is the first in the world to succeed in constructing artificial cell nuclei by injecting purified DNA solution instead of sperm into living mouse eggs. Their findings are published in ...

Researchers have used advanced microscopy and computational modeling to show how herpesvirus infection affects host-cell nucleus structure.

When cancer cells are physically squeezed, they mount an instant, high-energy defense by rushing mitochondria to the cell nucleus, unleashing a surge of ATP that fuels DNA repair and survival. This ...