Type VI secretion systems (T6SS) are sophisticated nanomachines that bacteria employ to inject effector proteins directly into neighbouring cells. These systems are structurally reminiscent of ...
Gut bacteria aren’t just passive passengers—they can actively send proteins straight into our cells. Using microscopic injection systems, even harmless microbes can influence immune responses and ...
Now Niederweis and colleagues at the University of Alabama at Birmingham describe the mechanism of secretion and trafficking of that toxin, TNT, which is the major cytotoxicity factor for the pathogen ...