Now, in a study in zebrafish and human heart muscle cells, researchers show that a tiny deletion in the A-band of titin — the loss of just nine amino acids out of more than 27,000 to 35,000 amino ...

A team at the Centro Nacional de Investigaciones Cardiovasculares (CNIC) has developed an innovative method known as TEVs-TTN, for studying the specific mechanical functions of proteins through their ...

If someone’s in heart failure, that means their heart is no longer able to function well enough to meet their body’s needs. According to new research from the University of Missouri School of Medicine ...

In striated muscle, the giant protein titin spans the entire length of a half-sarcomere and extends from the backbone of the thick filament, reversibly attaches to the thin filaments, and anchors to ...