Return of Function after Spinal Cord Transection has been a perennial problem. In the 1950s and 1960s the Russians reported success in Man using Trypsin and other agents. The reports made great ...

A study by Massachusetts General Hospital (MGH) investigators has found, for the first time in humans, that patients with chronic sciatica - back pain that shoots down the leg - have evidence of ...

Boosting communication between the spinal nerves and the muscles using the spinal cord stimulation reverses spinal muscle atrophy (SMA) progression and could be applied to other motoneuron diseases, ...

An experimental cancer drug can regenerate damaged nerves following spinal trauma in mice and rats. The corresponding report was published in Clinical and Translational Medicine. Spinal cord injury ...

Interpretation of clinical findings of BPI in newborns depends on knowledge of peripheral nervous system (PNS) structures and physiology. All nervous system structures originate from the embryonic ...

Injury to the spinal cord triggers a cascade of biological events that unfold within seconds and that proceed for months or even years. The events affect three major bodily systems: the nervous system ...

A spinal cord injury (SCI) is the occurrence of an acute traumatic damage to the spinal cord or nerves roots within the spinal column, including the cauda equina, that results in temporary or ...

A 46 year-old woman presented with pain in the neck for several months followed by a rapidly progressive quadriparesis over two days. Schwannoma: (Left) T2-weighted sagittal MRI of the cervical spine; ...

This Journal feature begins with a case vignette highlighting a common clinical problem. Evidence supporting various strategies is then presented, followed by a review of formal guidelines, when they ...