In past decades, catalytic cross-coupling reactions between organic halides and organometallic reagents to construct carbon–carbon bond have achieved a tremendous progress. However, organolithium ...

It would be highly advantageous to substitute aryl halides for the organometallic partner in addition to heteroarenes because it could dramatically increase the number and types of molecules that can ...

Aryl halides*1) with a benzene ring directly bonded to a halogen atom are readily available and chemically stable, so they are used as a source of benzene rings in organic synthesis. For example, a ...

Light exposure can trigger the seminal, 110-year-old Ullmann reaction—which typically forges C–N bonds via heat and a copper complex—showing that the reaction can proceed via single-­electron transfer ...

Alternatives to expensive palladium catalysts are gaining acceptance for commercial API synthesis. Cross-coupling reactions enable the synthesis of complex building blocks and intermediates with ...

The importance of aryl sulfides in biologically active compounds has led chemists to develop methods to synthesize them from carbon-sulfur bond forming reactions. The conventional reaction, however, ...