Future Oncol. 2013;9(11):1609-1622. The authors have no relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the ...

image: Researchers from IDIBELL have shown that pharmacological and genetic inhibition of RANK/RANKL signaling pathway leads to a significant reduction in recurrences and metastases in breast cancer ...

An evaluation of bone marrow stromal-derived growth factor-1 and interleukin-8 levels in patients with stage I-III breast cancer with disseminated tumor cells. This is an ASCO Meeting Abstract from ...

Rather than completely blocking all downstream signals, the peptide developed in this study focuses on inhibiting the activation of p38-MAPK. This is enough to downregulate the development of mature ...

Drinking milk helps your bones grow big and strong, but what if direct exposure to light could help, too? Now, researchers from Japan report that lighting up bone tissue could help treat bone disease.

Isolation and expansion of circulating tumor cells (CTC) from melanoma patients using a novel cell culture technique. This is an ASCO Meeting Abstract from the 2012 ASCO Annual Meeting I. This ...

Expert Rev Endocrinol Metab. 2009;4(6):639-650. Osteoporosis results in over nine million fractures per year at a cost of more than US$50 billion. Bone mass and strength are maintained by the bone ...

3 Centre for Sport & Exercise Medicine, William Harvey Research Institute, Queen Mary, University of London-John King Centre for Leg Pain, London Independent Hospital, London 4 Centre for Sport & ...

Researchers have revealed that RANKL expressed by osteocytes is essential for the bone remodeling during orthodontic tooth movement. This result can facilitate the development of novel therapeutic ...

Bone-destructive diseases such as osteoporosis and chronic inflammatory arthritis affect millions of people worldwide, causing pain, fractures, and decreased quality of life. These conditions often ...