Charge is a critical property of proteins, nucleic acids, and nanoparticles, influencing biological processes, colloidal stability, and aggregation. 1-3 While charge can be quantified in various ways, ...
The primary components of LNP–RNA are ionizable lipids, cholesterol, PEGylated lipids, and phospholipids, which together form the nanoparticle, along with the active pharmaceutical ingredient, RNA.