In the early stage of pharmaceutical product development, the rate-determining step has shifted from the synthesis phase to the analysis phase. There is a need for innovative techniques that allow for ...

Identifying crystal form is an ongoing challenge in the pharmaceutical industry. Process and storage conditions can result in polymorphic conversions which turn a stable, efficacious form of a drug ...

Polymorph screening is a critical step in developing an active pharmaceutical ingredient for a pharmaceutical formulation. The solid-state properties of an active pharmaceutical ingredient (API) play ...

MOST MAJOR DRUG FIRMS have a horror story in which a crystalline form, or polymorph, of a drug candidate suddenly appears or disappears, to the detriment of the development process. A polymorphic ...

TTP LabTech announced that it had successfully completed a major laboratory automation project with AstraZeneca. The project, which took over three years to complete, involved the design and build of ...

Polymorph farming on a chip is a promising strategy for rapid polymorph discovery by transforming crystallization?crystal isolation?characterization into one time-efficient step. Polymorph farming on ...

"TAKE TWO ASPIRIN and call me in the morning," the medical adage goes. To most people, this means simply washing down two tablets. Until late 2005, "take two aspirin" didn't have any different ...