This integrated approach, combining histological analysis and single-nucleus RNA sequencing, revealed that the senescence and depletion of nucleus pulposus progenitor cells (NPPCs) represent ...

Herniated nucleus pulposus (HNP), also referred to as a herniated disc, is a common spine pathology that occurs approximately 95% of the time at the L4-L5 or L5-S1 level (Fisher et al., 2004; Asch et ...

A comprehensive review published in Spine Research synthesizes evidence on aggrecan, the core molecule responsible for hydration in spinal discs. The authors present the first comprehensive, 4-part ...

Researchers have developed a gel inspired by cow slime for patients suffering from disc herniation. By adding the mucin gel immediately after surgery, it is possible to create a protective barrier ...