Scientists reveal a surprising new function of Notch protein that contrasts with the one known to date. Scientists headed by ICREA researcher Marco Milán, at the Institute for Research in Biomedicine ...
A novel gene called rumi regulates Notch signaling by adding a glucose molecule to the part of the Notch protein that extends outside a cell, said researchers from Baylor College of Medicine in ...
(Philadelphia, PA) – Researchers at the University of Pennsylvania School of Medicine have recently clarified the role of the Notch protein in T-cell development. T cells are required for many aspects ...
Proceedings of the National Academy of Sciences of the United States of America, Vol. 100, No. 9 (Apr. 29, 2003), pp. 5234-5239 (6 pages) Notch receptor signaling regulates cell growth and ...
We address the mechanisms underlying generation of skeletal muscle, smooth muscle, and endothelium from epithelial progenitors in the dermomyotome. Lineage analysis shows that of all epithelial ...
Notch is one of the most frequently mutated genes in chronic lymphocytic leukemia (CLL), the most common leukemia in adults in the United States. It is also often mutated in other common B cell tumors ...
Researchers have discovered how a molecule can help prevent certain types of brain tumors by recognizing and 'disarming' harmful proteins that cause them. Their study in fruit flies, published in the ...
Researchers at the University of Pennsylvania School of Medicine have recently clarified the role of the Notch protein in T-cell development. They found that Notch, a protein that regulates diverse ...
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