The modulation of neuronal glutamate receptors by phosphorylation is considered to be critical for synaptic plasticity. In particular, altering NMDA–type glutamate receptor properties by ...

One of several types of ligand-gated ion channel, the N-methyl-D-aspartate (NMDA) receptor transmits excitatory stimuli in the brain. When calcium flows through this channel, neural plasticity happens ...

Researchers have obtained images of the NMDA receptor in active, non-active, and inhibited states. Understanding how NMDA receptors activate is critical in designing novel therapeutic compounds for ...

Drugs that act on NMDA (N-methyl-D-aspartate) receptors, which are essential for learning, memory and moment-by-moment consciousness, are key for treating neuropsychiatric disorders. These drugs were ...

Excitatory amino acid receptors of the N-methyl-D-aspartate (NMDA) subtype are ligand-gated cation-selective ion channels. The unusual properties of NMDA receptors, and particularly of their channel, ...

Depressed teenager The designation is supported by data from a phase 2 study, which showed that REL-1017 produced rapid, robust, and sustained antidepressant effects vs placebo. The Food and Drug ...

For the first time, researchers in the lab of CSHL Professor Hiro Furukawa have been able to track each atom in the NMDA receptor, an important brain protein, as it transmits or inhibits neural ...

For the first time, researchers in the lab of CSHL Professor Hiro Furukawa have been able to track each atom in the NMDA receptor, an important brain protein, as it transmits or inhibits neural ...