Boston-based PerkinElmer Life and Analytical Sciences has released the prOTOF™ 2000, the first commercially available matrix-assisted laser desorption/ionization-time of flight (MALDI-TOF) mass ...

Although MALDI was originally used for the analysis of peptides and proteins, it now plays an important role in biomarker discovery, genotyping, identification of microorganisms, lipidomic analysis, ...

Matrix-assisted laser desorption/ionization (MALDI) and electrospray ionization (ESI) mass spectrometry has become an important tool in the life sciences. Recently, mass spectrometry methods have been ...

In order to design and develop new pharmaceutical compounds, the distribution of drugs and their metabolites in tissues must be determined to gain in-depth knowledge of the uptake of a drug into its ...

Several considerations are necessary to prepare MALDI IMS samples, including section thickness, tissue washes, and matrix selection and application, which are generally optimized empirically for each ...

Single-cell MALDI mass spectrometry (MS) imaging resolution is currently limited by the size of laser spot diameter, matrix crystal size/homogeneity, displacement of analytes during matrix deposition, ...

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MALDI time-of-flight mass spectrometry (MALDI-TOF MS) has become a widely used tool for the classification of biological samples. The complex chemical composition of pollen grains leads to highly ...

Watch this live demo from Bruker's lab to see the MALDI MS polymer analysis workflows from beginning to end. We will showcase several different Bruker MALDI instruments featuring advanced new ...

Perhaps no tool has been as instrumental to the proteomics revolution as the mass spectrometer. With the ability to deconvolute highly complex mixtures over a wide range of abundance levels, these ...

Inching towards precision medicine for multiple myeloma with causal network models. This is an ASCO Meeting Abstract from the 2019 ASCO Annual Meeting I. This abstract does not include a full text ...

Chemical analysis is a critical need in our high-tech industrial world. Mass spectrometry, with its high sensitivity and high selectivity, occupies a pivotal role in the detection and quantitation of ...