Researchers report a unique skeletal structure in the fins of a tetrapod-like fossil fish. Living four-limbed vertebrates, or tetrapods, exhibit a common skeletal pattern in the proximal part of their ...

LA JOLLA, Calif., June 9, 2009 -- Gregg Duester, Ph.D., professor of developmental biology at Burnham Institute for Medical Research (Burnham), along with Xianling Zhao, Ph.D., and colleagues, have ...

In 1978, Temtamy and McKusick classified isolated, non-syndromic Polydactyly and syndactyly, using a logical anatomical approach, into five distinct types for each group. Since then, there have been ...

Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, No. 44 (Nov. 4, 2008), pp. 16982-16987 (6 pages) Sonic hedgehog (Shh) plays an integral role in both the ...

Limb patterning usually refers to the shaping of hands and feet, which directly involve the fingers and toes respectively. Studies have revealed some key genes, among which the Hox genes are ...

An amputated salamander limb regenerates the correct number of segments. Models explaining limb regeneration were largely distinct from those for limb development, despite the presence of common ...

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Axolotls can regrow lost limbs, again and again, making them appealing to scientists who want to understand regeneration. Stephen Dalton/Minden Pictures/Corbis As amphibians go, axolotls are pretty ...

A new publication offers an extensive examination of clubfoot, a congenital deformity known as congenital talipes equinovarus (CTEV), affecting about 0.3% of all live births. Clubfoot is characterized ...