Against expectations, critically ill people in cardiogenic shock fared similarly receiving one widely used inotrope or another in the small DOREMI trial. Patients had the same clinical outcomes on ...

Background and aims: Variations in inotrope changeover technique can contribute to deviations in blood pressure, heart rate, internal bleeding and in extremis, death (Sheppard, 2001; Crisp, 2002; ...

French centers tested the calcium-sensitizing inotrope levosimendan in patients with severe but potentially reversible cardiogenic shock recently put on VA-ECMO. Early levosimendan did not facilitate ...

Reduction in the frequency of hospitalizations, by delaying additional episodes of acute decompensated heart failure; and Weaning patients with severe heart failure who are currently dependent on ...

Some heart failure clinics are offering outpatients infusions of inotropes, most often with milrinone, despite overwhelming evidence that the drugs are neither safe nor effective, according to a ...

One of the most frequently asked questions related to the use of these medications during rounds is whether there is a given drug or a combination of drugs that would effectively treat hypotension and ...

For critically ill people with acute cardiogenic shock on advanced mechanical life support, IV levosimendan came up short when tested in a modest-sized randomized trial. The calcium-sensitizing ...