MIAPE-CC covers the use of columns for protein or peptide separation, with a view to supporting the sharing of best practices, validation of results, discovery of results and sharing of experimental ...

Flash column chromatography was developed in 1978 as an alternative method to long column chromatography. The method aims to isolate a component from a mixture and thereby purify it. It was built from ...

In the past few decades, marine natural products bioprospecting has yielded a considerable number of drug candidates. Two marine natural products have recently been admitted as new drugs: Prialt (also ...

Downstream bioprocessing steps have long been a challenge to drug manufacturers, particularly the chromatography step for purification of monoclonal antibodies (mAbs). The complexity of traditional ...

In the present study myoglobins isolated from several kinds of abnormal muscle have been compared to normal adult and fetal myoglobins by means of methods developed for the characterization of normal ...

Generally, in protein and peptide analyses, knowing a molecule’s oligomeric state is useful in determining whether the protein exists in its biologically active form. To this end, the first step ...

Crude oil is an unruly soup of tens of thousands of organic compounds, and this diversity makes it difficult to pick out individual molecules from the crowd for analysis using standard tools such as ...

Chromatography is an analytical technique that is used to separate and analyze complex mixtures. Chromatography works by distributing the components of a mixture between two phases, known as the ...

Advanced analytics and modeling can be used to predict downstream failures, allowing for corrective action before batches are lost. In the biopharmaceutical industry, quality and consistency are two ...

Liquid chromatography (LC) systems are the backbone of laboratories within the pharmaceutical and biopharmaceutical industries. As an essential piece of equipment for bio-therapeutic analysis, they ...