Within the human brain, movement is coordinated by a brain region called the striatum, which sends instructions to motor neurons in the brain. Those instructions are conveyed by two pathways, one that ...

Researchers discover that the phosphorylation of a newly identified protein kinase substrate downstream of the dopamine signaling pathway regulates the brain reward behavior. The nucleus accumbens, ...

In a recent study published in Nature Neuroscience, a group of researchers explored how the cerebellum directly affects dopamine release in the substantia nigra compacta (SNc). While the cerebellum's ...

A growing body of neuroscience research is revealing that the brain’s ability to learn and its ability to move depend on the ...

ADHD is the most common neurobiological disorder in children. The key word being neurobiological. When in the throes of raising a neurodivergent child, it’s easy to forget that their behavior is ...

A finding by neuroscientists could open doors to new treatments for a range of psychiatric and neurological disorders attributed to dysfunctions in specific dopamine pathways. A finding by a ...

Tremor in Parkinson’s may follow a different biological pathway than previously thought, suggesting a more intricate disease ...

A Finnish clinical imaging study shows that rest tremor in Parkinson's disease is not explained by greater dopamine loss.

For decades, scientists have understood that when a person perceives something as pleasurable, dopamine is released in their brain. Hear a favorite song come on the radio? Dopamine time. See the ...

For decades, treatment of Parkinson’s disease has centered on replacing dopamine, the neurotransmitter whose decline drives ...

One part of the basal ganglia, known as the nucleus accumbens (NAc), is composed of medium spiny neurons (MSNs). The MSNs, in which the dopamine D1 receptor (D1R) and dopamine D2 receptor (D2R) ...