An artist’s depiction of an artificially evolved enzyme breaking a silicon-carbon bond. [Caltech/Dow] For the first time, scientists have engineered an enzyme that can break the stubborn man-made ...

Recent trends in directed enzyme evolution focus on combining high-throughput screening methods with advanced biophysical tools and data-driven computational approaches. However, these methods pose ...

For the first time, scientists have engineered an enzyme that can break stubborn man-made bonds between silicon and carbon that exist in widely used chemicals known as siloxanes, or silicones. The ...

Researchers at MIT have made a major breakthrough in optimizing rubisco, a key enzyme in photosynthesis. By modifying a bacterial version of this molecule, they achieved a 25% higher catalytic ...

Directed evolution—a process in which a protein library is subjected to repeated rounds of mutation and selection to achieve desired properties—can improve the catalytic performance of computationally ...

The paper describing how engineered enzymes build lactams in this article has since been retracted (Science 2020, DOI: 10.1126/science.aba6100). Using directed evolution, chemists have engineered ...

Enzymes catalyze chemical reactions in organisms - without which life would not be possible. Leveraging AlphaFold2 artificial intelligence, researchers at Charité – Universitätsmedizin Berlin have now ...

Enzymes are molecular machines that carry out the chemical reactions that sustain all life, an ability that has captured the ...