The discovery of Hoogsteen base pairs, an alternative pairing mode to the canonical Watson–Crick structure, has significantly broadened our understanding of DNA dynamics. This conformation, in which ...

(Nanowerk Spotlight) Hydrogen bond base pairing forces are essential for the mechanisms associated with DNA stability. Despite attracting great research attention, this fundamental interaction has ...

Although the information that can be crammed into a genome is remarkably complex, the molecule underlying it all obeys remarkably simple rules. In every creature we’ve studied, there are four bases ...

The genome sustains so much wear and tear, much of it hardly noticeable, that even the small portion of DNA damage that stays unrepaired far exceeds our inventory-taking abilities. Taking stock of DNA ...

DNA with three or more base pairs could find broad applications in a number of fields, including biotechnology, medicine, data storage, and security. Instead of just the canonical base pairs “G-C“ or ...

Scientists from Oxford's Radcliffe Department of Medicine have achieved the most detailed view yet of how DNA folds and functions inside living cells, revealing the physical structures that control ...

Over just a few short years the CRISPR gene-editing technique has revolutionized science, affecting everything from medicine to agriculture. Two new breakthrough studies have just been published ...

Molecular models are a tried-and-tested tool for teaching chemistry to students of all ages. By enabling users to visualize the three-dimensional structure of a molecule and how its atoms are arranged ...

The building block of life is often heralded as the cornerstone of a new generation of electronic devices and computers, but the electronic properties of DNA remain highly controversial. 1 Back to ...

ASU researchers have expanded on the capabilities of DNA origami to construct arbitrary two- and three-dimensional shapes, mimicking those often found in nature. The research is featured in the April ...