The cytochrome P450 (CYP) enzymes are a protein superfamily involved in the synthesis and metabolism of drugs, toxins and normal cellular components. The CYP family of enzymes have been identified in ...

Cytochrome c is a pivotal haemoprotein that resides within the mitochondrial intermembrane space, where it fulfils essential roles in cellular respiration and the regulation of apoptosis. Functioning ...

Figure 1: Outline of the catalytic cycle and the structure of cytochrome c oxidase. Figure 2: Absorbance difference spectra demonstrating the generation and decay of the one-electron reduced state E.

Despite their fundamental differences, plants, animals, and fungi share certain metabolic processes. Biologists at the U.S. Department of Energy's (DOE) Brookhaven National Laboratory have discovered ...

Proceedings of the Royal Society of London. Series B, Biological Sciences The Royal Society is a self-governing Fellowship of many of the world's most distinguished scientists drawn from all areas of ...

Clopidogrel requires transformation into an active metabolite by cytochrome P-450 (CYP) enzymes for its antiplatelet effect. The genes encoding CYP enzymes are polymorphic, with common alleles ...