Scientists have dedicated their lives to finding a cure for cancer. America became a science hub for cancer research, particularly after President Richard Nixon declared the “war on cancer” in 1971.

Patients with high-grade serous ovarian cancer will often initially respond to surgery and chemotherapy, with approximately 80% exhibiting recurrence and developing chemotherapy resistance. There is a ...

Immune Checkpoint Blockade (ICB) has reshaped cancer care and can deliver durable remission in malignancies such as melanoma and non-small cell lung cancer.

A study has revealed why some patients don't respond to immune checkpoint blockade (ICB) therapy for solid cancer tumors and identifies a new combination treatment. Publishing in Nature Immunology, ...

Checkpoint inhibitors are antibody-based cancer therapies that unlock the immune system’s natural ability to fight cancer. These treatments work by blocking special proteins called immune checkpoints, ...

In a study published in the journal Biofunctional materials, researchers from the Wits Advanced Drug Delivery Platform (WADDP) Research Unit, Department of Pharmacy and Pharmacology, and the Division ...

In a recent study published in Cell, a group of researchers elucidated the shared immune tolerance mechanisms in cancer and pregnancy, focusing on the role of progestogen-induced B7 Homolog 4 (B7-H4) ...

The MSI-H/dMMR phenotype in men with advanced PCa is associated with greater likelihood of a durable response to PD-1/PD-L1 inhibitors. Immune checkpoint blockade may benefit men with advanced ...