With the help of zinc reagents, chemists have found a loophole in rules that govern additions to chiral carbonyl compounds, a fundamental reaction in organic synthesis. The work, presented on March 24 ...
Scientists at the Institute of Science Tokyo (Science Tokyo) have successfully realized the highly selective asymmetric 1,6 addition of aliphatic Grignard reagents to α,β,γ,δ-unsaturated carbonyl ...
The proposed method for anti-Michael addition in this study can enable one-step synthesis of α-substituted carbonyl compounds, which are commonly used in pharmaceuticals. Their study was made ...
In this review, our recent results on the concurrent cationic vinyl-addition and ring-opening copolymerization of vinyl ethers (VEs) and oxiranes are summarized, with particular emphasis on the ...
Carbonyls (C=O groups) are popular reactive handles. But carbonylation reactions, which create these useful groups by appending carbon monoxide to aryl halides or alkyl halides with the help of a ...
The proposed method for anti-Michael addition in this study can enable one-step synthesis of α-substituted carbonyl compounds, which are commonly used in pharmaceuticals.