SPOP is the most mutated protein in prostate cancer and plays a role in endometrial, uterine and other cancers. Despite this importance, how SPOP mutations drive cancer has been incompletely ...

Researchers have created a tool that maps how breast cancer grows in previously unseen detail, and highlights how the cells around the tumor may be the key to controlling the spread of disease. New ...

Bioengineers at the University of Texas (UT) at Austin have developed a portable, miniature microscope designed to improve the ability to detect early-stage oral cancer and improve surgical margin ...

Chemotherapy is a powerful weapon against cancer, but certain cells resist treatment by entering a dormant stage called senescence. These therapy-induced senescent (TIS) cells may become resistant to ...

Pancreatic ductal adenocarcinoma (PDAC) is a fatal disease with rising incidence and a remarkable resistance to current therapies. One of the main reasons for this therapeutic failure is the tumor's ...

Are virtual biopsies the key to earlier and more accurate detection of oral and head and neck cancers? While several next-generation optical techniques -- including optical coherence tomography (OCT), ...

LMU researchers have discovered how the interplay between a key protein and an endolysosomal ion channel promotes tumor development in skin cancer. Melanoma arising from pigment-producing cells known ...

Understanding how tumors change their metabolism to resist treatments is a growing focus in cancer research. As cancer cells ...

Researchers from the University of Illinois at Urbana-Champaign have invented a novel live-cell imaging method that could someday help biologists better understand how stem cells transform into ...

Using advanced imaging technology, scientists have provided an unprecedented understanding of the BRCA1-BARD1 protein complex, which is often mutated in patients with breast or ovarian cancer. Their ...