Thiazide diuretics are used to prevent the recurrence of calcium-containing kidney stones. The ability of these drugs to reduce urinary calcium excretion has a key role in this process. Although ...
The gene KCTD1 directs production of a protein that functions in the kidney to maintain a normal balance of magnesium and calcium in blood. Loss of KCTD1 impairs the ability of the kidney to properly ...
These receptors comprise a subfamily (family C) of the G-protein-coupled-receptor superfamily. They share large extracellular domains, which sense their respective ligands. G-protein-coupled receptors ...
HYDROCHLOROTHIAZIDE (6-chloro-7-sulfamyl-3,4,dihydro-l,2,4, benzothiadiazine-1,1,-dioxide) is the 3,4,dihydro derivative of chlorothiazide wherein the 3,4 double bond is saturated by two hydrogen ...
A right kidney stone as seen on abdominal CT Some risk factors are unavoidable, but adjusting your patient's diet and addressing comorbidities can prevent excruciating episodes. The time-honored ...
Renal Tubular Acidosis and Renal Potassium Wasting Acquired as a Result of Hypercalcemic Nephropathy
THE earliest lesions of certain types of experimental nephrocalcinosis involve the distal portions of the renal tubules and the collecting ducts. 1,2 Disturbances in renal tubular function might ...
Hypertension is an important public health problem affecting more than 50 million individuals in the US alone. The most common form, essential hypertension, results from the complex interplay between ...
BOSTON - While investigating the underlying causes of a rare skin disorder, a researcher at Massachusetts General Hospital (MGH) discovered a previously unknown mechanism in the kidneys that is ...
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