Following a double-strand DNA break, an enzyme called PARP1 helps hold the two strands together —like superglue— and creates a safe zone for other proteins to come repair the damage. We don’t exactly ...

Although DNA is tightly packed and protected within the cell nucleus, it is constantly threatened by damage from normal metabolic processes or external stressors such as radiation or chemical ...

The DNA in our cells is constantly damaged, with the most severe being the simultaneous breakage of both strands that compose it. In a study published in Nature Communications, scientists reveal in ...

They have used 'magnetic tweezers', a nanotechnology technique that measures how much a single DNA molecule is stretched. The work is published in Cell Reports. "Understanding this mechanism could ...

Researchers have revealed the structural mechanisms of a major DNA repair pathway in human cells. The research, published today as a Reviewed Preprint in eLife, is described by the editors as a ...