Several methods have been developed to site-selectively introduce probes into proteins in live cells: chemical modification of amino acid side chains 6, biosynthetic fusion of fluorescent proteins 7 ...

In a recent study published in Scientific Reports, researchers performed a structural bioinformatics analysis to evaluate the binding energy of the severe acute respiratory syndrome coronavirus 2 ...

"Through this process, we were able to achieve highly efficient and selective affinity labeling of carbohydrate-binding proteins in cell lysate," Sakurai said. "We will apply the new method in target ...

In ESR, a spin label is added to the target site using cysteine substitution. This is followed by modifying the sulfhydryl group with a paramagnetic nitroxide reagent. The ESR then provides ...